I feel a depressing amount of potential was ultimately wasted by the writers just not leaving terrible ideas and habits well enough alone, but they remain an OTP to this day. They’re so cute and deserved much better than what they got (especially Trixie).
My takes on them don’t differ much from the canon. Just some colored hooves and curved horns, with a few markings here and there! Oh, and they’re married and traveling Equestria together, because that would have been great. Let Glim-Glam properly spread her wings and leave the nest to actually apply those friendship lessons, Twi.