This one is based of an idea I had. Since Trixie was originally supposed to be a man before she was a women, I thought that it would be an interesting idea to use.
Trixie on the left, is with Twilight, telling her that she had wanted to be a man, instead of a girl, and was worried that Twilight might not love her anymore, due to these changes. Twilight told her that it is ok, as she would love Trixie no matter what her gender was. The pic on the right is the aftermath of Trixie changing gender. She is now known as Trevor. Here it has Twilight and Trevor embracing, with Twilight telling him that she will always love him.
I hope that this was ok. I’m sorry if this is seen as offensive to any trans people out there.
MLP belongs to Hasbro.