Top Row: Big Macintosh, Fluttershy, and Tempest Shadow
Bottom Row: Nimble Nectarine, Ladybug and Bear Hug
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Big Macintosh and Fluttershy had Nimble as a late teenagers, (Before him and Sugar Belle would have gotten married in canon) and broke up shortly before his birth. They coparented well in his young childhood years but they started disagreeing on parenting during his older childhood, preteens and worse so in his teens. Big Mac and Nimble now have an extremely strained relationship, Fluttershy and Mac much more so.
Fluttershy started spending more time with Tempest and Luna during their group therapy sessions for anxiety. Twilight suggested it all her friends who struggled with anxiety, she herself attended regularly too. But, they started bonding over their mutual distrust of new ponies and it went from there. They really started to like and then love one another, they now both live together with their two kids. Tempest struggles with her youngest being a unicorn and having magical outbursts.